- This will be the second Illumination Entertainment film to be based on a Dr. Seuss book, after The Lorax (2012).
- The film was originally going to be released on November 10, 2017, but it was changed to November 9, 2018.
- This will mark the second film to be based on How the Grinch Stole Christmas!, after the 2000 live-action film starring Jim Carrey.
- This is the first Illumination Entertainment's Christmas film.
- This will be Illumination Entertainment's first film to be released in November.
- The third Illumination Entertainment's musical film, after The Lorax and Sing.
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